RAS Gene Hot-Spot Mutations in Canine Neoplasias
نویسندگان
چکیده
منابع مشابه
Absence of ras-gene hot-spot mutations in canine fibrosarcomas and melanomas.
Point mutations within ras proto-oncogenes, particularly within the mutational hot-spot codons 12, 13 and 61, are frequently detected in human malignancies and in different types of experimentally-induced tumours in animals. So far little is known about ras mutations in naturally occurring canine fibrosarcomas or K-ras mutations in canine melanomas. To elucidate whether ras mutations exist in t...
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ژورنال
عنوان ژورنال: Journal of Heredity
سال: 2005
ISSN: 0022-1503,1465-7333
DOI: 10.1093/jhered/esi121